Results 91 to 100 of about 3,575 (254)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Linear Forms in Logarithms and Fibonacci Numbers
, 2019 The main work included in these pages is from a paper co-written by myself and my brother, Simon Earp-Lynch, under the supervision of Omar Kihel, pertaining to Diophantine triples of Fibonacci numbers.
Earp-Lynch, Benjamin
core
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
An Explicit Bound for the Logarithmic Integral Derived via Linear Forms in Logarithms
This paper establishes an explicit conditional upper bound for the Eulerian logarithmic integral by bridging transcendental and analytic number theory. Specifically, we apply the Baker-Matveev method for linear forms in logarithms to a primorial-based Diophantine system.
+8 more sources
Mock-Modular Forms of Weight One [PDF]
, 2013 In this thesis, we will study mock-modular forms of weight one and their Fourier coefficients. In particular, we will concentrate on the mock-modular forms whose shadows are dihedral newforms arising from ray class group characters of imaginary quadratic
Li, Yingkun
core
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
On the Kernel of the Symbol Map for Multiple Polylogarithms [PDF]
, 2012 The symbol map (of Goncharov) takes multiple polylogarithms to a tensor product space where calculations are easier, but where important differential and combinatorial properties of the multiple polylogarithm are retained.
RHODES, JOHN,RICHARD
core
Transcendence of certain infinite sums involving rational functions [PDF]
, 2001 We show that it follows from results on linear forms in logarithms of algebraic numbers such as where χ is any non-principal Dirichlet character and (Fn∞n=0 the Fibonacci sequence, are ...
Genčev, Marian +6 more
core +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source