The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Multiscale modelling of birth-death processes. [PDF]
Kimpson T +3 more
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Machine learning methodology using a masked neural network for robust genetic risk score calculation from noisy and missing data. [PDF]
Squires S, Weedon MN, Oram RA.
europepmc +1 more source
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Uncertainty aware resilience enhancement of energy hub integrated distribution networks under heterogeneous disturbance events. [PDF]
Emaratkar S, Moradlou M, Nazarian P.
europepmc +1 more source
Synthetic Seismic Accelerogram Generation via Wavelet- Decomposed Conditional Generative Adversarial Networks. [PDF]
Rocca A, Laura L, Parrillo M.
europepmc +1 more source
Bayesian Conditional GAN for Unsupervised Anomaly Detection in Structural Health Monitoring Time-Series Dataset. [PDF]
Alemu YL +7 more
europepmc +1 more source
Pollutant emissions of conventional energy generators with increased renewable energy sources: a 2030 New York case study. [PDF]
Ramirez AAF, Lamadrid LAJ.
europepmc +1 more source
Avatar generator: a tool for prediction of three-dimensional humanoid avatars from manual anthropometric measurements. [PDF]
Minetto MA +9 more
europepmc +1 more source

