Results 71 to 80 of about 51,458 (317)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

High-Order Integral Equation Methods for Diffraction Problems Involving Screens and Apertures [PDF]

open access: yes, 2012
This thesis presents a novel approach for the numerical solution of problems of diffraction by infinitely thin screens and apertures. The new methodology relies on combination of weighted versions of the classical operators associated with the Dirichlet ...
Lintner, Stéphane Karl
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Efficient numerical methods for Volterra integral equations of Hammerstein type [PDF]

open access: yes, 2006
Volterra integral equations (VIEs) are the mathematical model of many evolutionary problems with memory arising from biology, chemistry, physics, engineering.
Del Prete, Ida
core  

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Convergence of a collocation scheme for a retarded potential integral equation [PDF]

open access: yes, 2003
Time domain boundary integral formulations of transient scattering problems involve retarded potential integral equations (RPIEs). Solving such equations numerically is both complicated and computationally intensive, and numerical methods often prove to ...
Duncan, D.B.
core  

Almost sure subexponential decay rates of scalar Ito-Volterra equations. [PDF]

open access: yes, 2004
The paper studies the subexponential convergence of solutions of scalar Itˆo-Volterra equations. First, we consider linear equations with an instantaneous multiplicative noise term with intensity .
Appleby John A. D.   +2 more
core   +1 more source

Integral equation in the theory of optimal speed of linear systems with constraints

open access: yesВестник КазНУ. Серия математика, механика, информатика, 2020
Boundary-value problems with phase constraints for linear ordinary differential equations are considered. The necessary and sufficient conditions for the existence of a solution to the boundary value problems of linear ordinary differential equations ...
S.А. Aisagaliev   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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