Results 111 to 120 of about 24,946,429 (302)

Goodness-of-fit tests in mixed models. [PDF]

Mixed models, with both random and fixed effects, are most often estimated on the assumption that the random effects are normally distributed. In this paper we propose several formal tests of the hypothesis that the random effects and/or errors are ...
Claeskens, Gerda, Hart, Jeffrey D.
core  

Prediction in linear mixed models

, 2004
Following estimation of effects from a linear mixed model, it is often useful to form predicted values for certain factor/variate combinations. The process has been well defined for linear models, but the introduction of random effects into the model ...
Gogel, Beverley, Gogel, B., Thompson, Robin, Welham, Sue, Gilmour, A., Cullis, Brian R., Gilmour, Arthur, Welham, S. J., Thompson, R., Cullis, B. R.   +9 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Microbiome variations induced by delta9-tetrahydrocannabinol predict weight reduction in obese mice

Frontiers in Microbiomes
IntroductionObesity and high-fat diets induce consistent alterations in gut microbiota composition. Observations from epidemiological reviews and experiments also illustrate weight regulation effects of delta9-tetrahydrocannabinol (THC) with microbiome ...
Avi Kaye, Matthew Rusling, Amey Dhopeshwarkar, Parhesh Kumar, Lauren Wagment-Points, Kenneth Mackie, Li-Lian Yuan   +6 more
doaj   +1 more source

Identifiability of linear mixed effects models

Electronic Journal of Statistics, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Morphological set: Fixed effects from the linear-mixed effects model.

, 2019
Morphological set: Fixed effects from the linear-mixed effects model.
Laura Anna Ciaccio (8173494), Gunnar Jacob (8173497)   +1 more
core   +1 more source

Effects of Salinity and Temperature on Survival, Growth, and Food Intake of Ramshorn Snail (Helisoma anceps)

Ecology and Evolution
Understanding the salinity tolerance of Helisoma anceps is crucial for its application in aquaculture systems, particularly at the Fish Conservation and Culture Laboratory (FCCL), where the species is used to maintain water quality in Delta and Longfin ...
Szu‐Han Chen, Tien‐Chieh Hung
doaj   +1 more source

Stochastic Expectation Maximization Algorithm for Linear Mixed-Effects Model with Interactions in the Presence of Incomplete Data. [PDF]

Entropy (Basel), 2023
Zakkour A, Perret C, Slaoui Y.
europepmc   +1 more source