Results 221 to 230 of about 1,982,495 (283)
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
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2014
Chapter Preview . We give a general discussion of linear mixed models and continue by illustrating specific actuarial applications of this type of model. Technical details on linear mixed models follow: model assumptions, specifications, estimation techniques, and methods of inference.
Antonio, K., Zhang, Y.
openaire +3 more sources
Chapter Preview . We give a general discussion of linear mixed models and continue by illustrating specific actuarial applications of this type of model. Technical details on linear mixed models follow: model assumptions, specifications, estimation techniques, and methods of inference.
Antonio, K., Zhang, Y.
openaire +3 more sources
2020
This chapter introduces linear mixed models, which have wide applicability in small area estimation due to their flexibility to combining different types of information and explaining sources of errors. Three of the most used fitting methods are presented under two parametrizations.
Domingo Morales +3 more
openaire +2 more sources
This chapter introduces linear mixed models, which have wide applicability in small area estimation due to their flexibility to combining different types of information and explaining sources of errors. Three of the most used fitting methods are presented under two parametrizations.
Domingo Morales +3 more
openaire +2 more sources
2007
Statistical models provide a framework in which to describe the biological process giving rise to the data of interest. The construction of this model requires balancing adequate representation of the process with simplicity. Experiments involving multiple (correlated) observations per subject do not satisfy the assumption of independence required for ...
Ann L, Oberg, Douglas W, Mahoney
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Statistical models provide a framework in which to describe the biological process giving rise to the data of interest. The construction of this model requires balancing adequate representation of the process with simplicity. Experiments involving multiple (correlated) observations per subject do not satisfy the assumption of independence required for ...
Ann L, Oberg, Douglas W, Mahoney
openaire +2 more sources