Results 1 to 10 of about 11,261,456 (259)

On non-negative estimation of variance components in mixed linear models [PDF]

open access: yesJournal of Advanced Research, 2016
Alternative estimators have been derived for estimating the variance components according to Iterative Almost Unbiased Estimation (IAUE). As a result two modified IAUEs are introduced.
Heba A. El Leithy   +2 more
doaj   +2 more sources

Fitting Linear Mixed-Effects Models Using lme4

open access: yesJournal of Statistical Software, 2015
Maximum likelihood or restricted maximum likelihood (REML) estimates of the parameters in linear mixed-effects models can be determined using the lmer function in the lme4 package for R. As for most model-fitting functions in R, the model is described in
Douglas Bates   +3 more
doaj   +2 more sources

partR2: partitioning R2 in generalized linear mixed models [PDF]

open access: yesPeerJ, 2021
The coefficient of determination R2 quantifies the amount of variance explained by regression coefficients in a linear model. It can be seen as the fixed-effects complement to the repeatability R (intra-class correlation) for the variance explained by ...
Martin A. Stoffel   +2 more
doaj   +2 more sources

BLMM: Parallelised computing for big linear mixed models

open access: yesNeuroImage, 2022
Within neuroimaging large-scale, shared datasets are becoming increasingly commonplace, challenging existing tools both in terms of overall scale and complexity of the study designs.
Thomas Maullin-Sapey, Thomas E. Nichols
doaj   +1 more source

Variational Bayesian Inference in High-Dimensional Linear Mixed Models

open access: yesMathematics, 2022
In high-dimensional regression models, the Bayesian lasso with the Gaussian spike and slab priors is widely adopted to select variables and estimate unknown parameters. However, it involves large matrix computations in a standard Gibbs sampler.
Jieyi Yi, Niansheng Tang
doaj   +1 more source

Polygenic modeling with bayesian sparse linear mixed models. [PDF]

open access: yesPLoS Genetics, 2013
Both linear mixed models (LMMs) and sparse regression models are widely used in genetics applications, including, recently, polygenic modeling in genome-wide association studies.
Xiang Zhou   +2 more
doaj   +1 more source

CytoGLMM: conditional differential analysis for flow and mass cytometry experiments

open access: yesBMC Bioinformatics, 2021
Background Flow and mass cytometry are important modern immunology tools for measuring expression levels of multiple proteins on single cells. The goal is to better understand the mechanisms of responses on a single cell basis by studying differential ...
Christof Seiler   +7 more
doaj   +1 more source

Bayesian Linear Mixed Models with Polygenic Effects

open access: yesJournal of Statistical Software, 2018
We considered Bayesian estimation of polygenic effects, in particular heritability in relation to a class of linear mixed models implemented in R (R Core Team 2018).
Jing Hua Zhao   +2 more
doaj   +1 more source

Generalized linear mixed models can detect unimodal species-environment relationships [PDF]

open access: yesPeerJ, 2013
Niche theory predicts that species occurrence and abundance show non-linear, unimodal relationships with respect to environmental gradients. Unimodal models, such as the Gaussian (logistic) model, are however more difficult to fit to data than linear ...
Tahira Jamil, Cajo J.F. ter Braak
doaj   +2 more sources

Linear Mixed Models: Gum and Beyond

open access: yesMeasurement Science Review, 2014
In Annex H.5, the Guide to the Evaluation of Uncertainty in Measurement (GUM) [1] recognizes the necessity to analyze certain types of experiments by applying random effects ANOVA models.
Arendacká Barbora   +4 more
doaj   +1 more source

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