Results 11 to 20 of about 604,878 (242)
CytoGLMM: conditional differential analysis for flow and mass cytometry experiments
BMC Bioinformatics, 2021 Background Flow and mass cytometry are important modern immunology tools for measuring expression levels of multiple proteins on single cells. The goal is to better understand the mechanisms of responses on a single cell basis by studying differential ...
Christof Seiler +7 more
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Bayesian Linear Mixed Models with Polygenic Effects
Journal of Statistical Software, 2018 We considered Bayesian estimation of polygenic effects, in particular heritability in relation to a class of linear mixed models implemented in R (R Core Team 2018).
Jing Hua Zhao +2 more
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Generalized linear mixed models can detect unimodal species-environment relationships [PDF]
PeerJ, 2013 Niche theory predicts that species occurrence and abundance show non-linear, unimodal relationships with respect to environmental gradients. Unimodal models, such as the Gaussian (logistic) model, are however more difficult to fit to data than linear ...
Tahira Jamil, Cajo J.F. ter Braak
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Fitting Linear Mixed-Effects Models Using lme4
Journal of Statistical Software, 2015 Maximum likelihood or restricted maximum likelihood (REML) estimates of the parameters in linear mixed-effects models can be determined using the lmer function in the lme4 package for R. As for most model-fitting functions in R, the model is described in
Douglas Bates +3 more
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Linear Mixed Models: Gum and Beyond
Measurement Science Review, 2014 In Annex H.5, the Guide to the Evaluation of Uncertainty in Measurement (GUM) [1] recognizes the necessity to analyze certain types of experiments by applying random effects ANOVA models.
Arendacká Barbora +4 more
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Subset Selection for Linear Mixed Models
Biometrics, 2022 AbstractLinear mixed models (LMMs) are instrumental for regression analysis with structured dependence, such as grouped, clustered, or multilevel data. However, selection among the covariates—while accounting for this structured dependence—remains a challenge. We introduce a Bayesian decision analysis for subset selection with LMMs. Using a Mahalanobis
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Model Selection in Linear Mixed Models
Statistical Science, 2013 Linear mixed effects models are highly flexible in handling a broad range of data types and are therefore widely used in applications. A key part in the analysis of data is model selection, which often aims to choose a parsimonious model with other desirable properties from a possibly very large set of candidate statistical models.
Müller, Samuel +2 more
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Bayesian Inference for Spatial Beta Generalized Linear Mixed Models [PDF]
Journal of Sciences, Islamic Republic of Iran, 2018 In some applications, the response variable assumes values in the unit interval. The standard linear regression model is not appropriate for modelling this type of data because the normality assumption is not met. Alternatively, the beta regression model
L. Kalhori Nadrabadi, M. Mohhamadzadeh
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Fast and flexible linear mixed models for genome-wide genetics. [PDF]
PLoS Genetics, 2019 Linear mixed effect models are powerful tools used to account for population structure in genome-wide association studies (GWASs) and estimate the genetic architecture of complex traits.
Daniel E Runcie, Lorin Crawford
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Accessible analysis of longitudinal data with linear mixed effects models
Disease Models & Mechanisms, 2022 Longitudinal studies are commonly used to examine possible causal factors associated with human health and disease. However, the statistical models, such as two-way ANOVA, often applied in these studies do not appropriately model the experimental design,
Jessica I. Murphy +2 more
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