FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Asymptotically Nonparametric Inference: An Alternative Approach to Linear Models [PDF]
, 1963 E. L. Lehmann
openalex +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Bite Me: Bark Stripping Showed Negligible Effect on Volume Growth of Norway Spruce in Latvia
PlantsOver the past few decades, increasing populations of cervid species in the Baltic region have reduced the quality and vitality of cultivated Norway spruce (Picea abies (L.) Karst.) stands.
Agnese Anta Liepiņa +7 more
doaj +1 more source
On Combinability of Information from Uncorrelated Linear Models by Simple Weighting [PDF]
, 1966 Frank B. Martin, George Zyskind
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Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Oxisol subsurface chemical attributes related to sugarcane productivity
Scientia Agricola, 2003 In spite of the great homogeneity found in the morphological characteristics of Oxisols, there is great chemical diversity in subsurface layers of these soils. Studies indicate that crop yield presents significant correlation with the chemical attributes
Marcos Guimarães de Andrade Landell +7 more
doaj
Genomic Prediction for Inbred and Hybrid Polysomic Tetraploid Potato Offspring
AgriculturePotato genetic improvement begins with crossing cultivars or breeding clones which often have complementary characteristics for producing heritable variation in segregating offspring, in which phenotypic selection is used thereafter across various ...
Rodomiro Ortiz +5 more
doaj +1 more source
Non-linear model of progressive electromagnetic waves in the presence of a magnetic field [PDF]
, 1964 C. Brossier
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Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source