Results 121 to 130 of about 590,268 (302)
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
On Some Analogues to Linear Combinations of Order Statistics in the Linear Model
The Annals of Statistics, 1973 We consider the general linear model with independent symmetric errors. In this context we propose and examine the large sample behavior of some estimates of the regression parameters. For the location model these statistics are linear combinations of order statistics.
openaire +3 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
S-estimation and a robust conditional Akaike information criterion for linear mixed models. [PDF]
We study estimation and model selection on both the fixed and the random effects in the setting of linear mixed models using outlier robust S-estimators.
Tharmaratnam, Kukatharmini +1 more
core
Semiparametric linear regression with censored data and stochastic regressors [PDF]
, 1994 We propose three new estimation procedures in the linear regression model with randomly-right censored data when the distribution function of the error term is unspecified, regressors are stochastic and the distribution function of the censoring variable
Mora, Juan
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Nonlinear impact of minimum wage on labor employment in China
Nonlinear EngineeringThis study examines the impact of increasing minimum wages, focusing primarily on their effect on employment. Our research involved analyzing the statistics of panel data, testing fixed effects and stationary, conducting linear regression, and ...
LYU Junhan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source