Results 51 to 60 of about 3,634,241 (247)
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Alexandria Engineering JournalFatigue cracking in hot mix asphalt (HMA) is a critical issue in flexible pavement maintenance, often leading to premature failure. Traditional fatigue tests are time-consuming and require significant manual effort.
Erkut Yalcin, Ragip Ince, Mehmet Yilmaz
doaj +1 more source
Selective targeting of NOTCH-1 for therapeutic purposes in xenograft models of T-acute lymphoblastic leukemia [PDF]
, 2013 T-cell acute lymphoblastic leukemia (T-ALL) is an heterogeneous disease, characterized by several genetic alterations and polymorphic clinical features both in children and adults.
Agnusdei, Valentina
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Advanced Engineering Materials, EarlyView.Low‐temperature imidization of PEG‐modified polyimide enables fully screen‐printed, roll‐to‐roll fabrication of flexible electrodes on PET substrates, delivering robust mechanical durability and reliable ECG/EMG signal performance for wearable electronics.
Akib Abdullah Khan, Jong‐Hoon Kim
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Advanced Engineering Materials, EarlyView.Different Al/Al bimetals with a single engineered interface reveal how mechanical mismatch governs fatigue crack growth under cyclic loading. Additionally, loading–unloading–reloading tests link the microyielding behavior to the fatigue crack growth resistance, while crack‐path analysis reveals toughening mechanisms at the interface, highlighting ...
Sebastian Vollath +2 more
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Fracture and Structural IntegrityThe compliance method was first applied to short rod specimens to determine the nonlinear fracture toughness of rock materials by ISRM (International Society for Rock Mechanics) in the 1980s. In this study, utilizing the techniques of the J-integral and
Ragip Ince, Erkin Eren
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Analysis of the mechanism of fatigue crack arrest in a cylindrical notched specimen
Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2018 The phenomenon of fatigue crack arrest in surface-hardened cylindrical specimens with stress concentrators is examined from the perspective of linear fracture mechanics.
V. P. Sazanov
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Advanced Engineering Materials, EarlyView.Schematic representation of modes of microcrack nucleation, growth and temporary arrestment at different boundaries, with the criteria for crack propagation in three scenarios: (1) large notch, (2) defect/small sharp notch, and (3) long crack. This work revisits and integrates results on the fatigue behavior of advanced bainitic steels (in particular ...
Lucia Morales‐Rivas
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Advanced Engineering Materials, EarlyView.Enhancing ultrasound transmission through an aberration layer exhibiting mismatched impedance with the surrounding medium possesses great implications in imaging and treatment. In this study, we show that a space‐coiling acoustic metamaterial with judiciously tailored structural profile can help improve impedance matching.
Maral Ghanami +4 more
wiley +1 more source
Design of a Multistable Finger Prosthesis with Programmable Metamaterials
Advanced Engineering Materials, EarlyView.This research article shows the development of a multistable programmble metamaterial for the use as a finger prosthesis. The material was designed on different hierarchical levels where the influence of geometrical parameters and combination of mechanical elements was explored.
Franziska Wenz +5 more
wiley +1 more source