Results 41 to 50 of about 3,634,241 (247)
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1997 Fatigue tests were carried out on notched and shouldered specimens of a cast stainless steel under rotating bending and reversed torsion. It is shown that the fatigue strength of a notched or a shouldered specimen having an arbitrary size under the two loading conditions can be predicted systematically based on the concept of the linear notch mechanics
NISITANI, Hironobu +3 more
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Notch signaling pathway in human vascular smooth muscle cell differentiation [PDF]
, 2006 Notch receptor-ligand interactions are a highly conserved mechanism, originally described in developmental studies using Drosophilae, that regulate inter-cell communication and dictate, in part, vascular smooth muscle cell (VSMC) fate in response to ...
Scheller, Agnieszka
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Polymer TestingThe increasing use of three-dimensional (3D) printed polymer components in critical applications, such as in aerospace, requires accurate approaches for measuring the special mode II fracture toughness.
Xiaodong Zheng +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1994 The maximum elastic stress in a cracked or notched body is not a unique parameter that controls the failure or fracture of the body. Therefore, we must determine the measure of severity in a cracked or notched body in order to predict the strength of real objects from the strength of specimens.
Nisitani, Hironobu, Fujisaki, Wataru
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
A study of Notch signalling in developmental angiogenesis [PDF]
, 2009 Blood vessel patterning during angiogenesis is a guided process. Endothelial tip cells located at the end of vascular sprouts are important for vessel guidance.
Phng, L.-K., Phng, L-K
core
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Examination of rotating bending fatigue of HIP-sintered SMF3035 by linear notch mechanics.
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1991 Fatigue tests of HIP'ed SMF3035 were conducted on specimens with a circumferential groove whose diameters were different. As a result, it is successfully confirmed that linear notch mechanics (LNM) is available for the examination of notch effects in the fatigue of HIP'ed SMF3035.
NISITANI, Hironobu +3 more
openaire +2 more sources