Results 91 to 100 of about 5,164,048 (315)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

A sequence of positive linear operators

open access: yesJournal of Numerical Analysis and Approximation Theory, 1995
Not available.
M. Ivan, I. Rașa
doaj   +2 more sources

Fixed Point Theorems for Middle Point Linear Operators in L1

open access: yesFixed Point Theory and Applications, 2008
We introduce the notion of middle point linear operators. We prove a fixed point result for middle point linear operators in L1. We then present some examples and, as an application, we derive a Markov-Kakutani type fixed point result for commuting ...
Anna Martellotti, Milena Chermisi
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

An Extension of Hypercyclicity for N-Linear Operators

open access: yesAbstract and Applied Analysis, 2014
Grosse-Erdmann and Kim recently introduced the notion of bihypercyclicity for studying the existence of dense orbits under bilinear operators. We propose an alternative notion of orbit for N-linear operators that is inspired by difference equations ...
Juan Bès, J. Alberto Conejero
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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