Results 51 to 60 of about 61,998,172 (203)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Norm and Numerical Radius Inequalities for Two Linear Operators in Hilbert Spaces [PDF]

open access: yes, 2008
Some inequalities for the norm and numerical radius of two bounded linear operators in Hilbert spaces are ...
Dragomir, Sever S
core   +2 more sources

Rellich-type Discrete Compactness for Some Discontinuous Galerkin FEM [PDF]

open access: yes
We deduce discrete compactness of Rellich type for some discontinuous Galerkin finite element methods (DGFEM) including hybrid ones, under fairly general settings on the triangulations and the finite element spaces.
KIKUCHI, Fumio
core  

Measures of Non-compactness of Operators for Banach Lattices [PDF]

open access: yes, 2013
Bu tez çalışması üç bölümden oluşmaktadır. İlk bölümde bir giriş yapılmış, ikinci bölümde, Banach uzayları, Banach örgüleri ve pozitif operatörler ile ilgili temel tanım ve teoremler ve ayrıca sınırlı lineer operatörlerin spektrum ve esaslı spektrum ...
Çalışkan, Begüm
core  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Convergence Properties of Certain Positive Linear Operators

open access: yes, 2019
The present paper deals with the modified positive linear operators that present a better degree of approximation than the original ones. This new construction of operators depend on a certain function defined on [0, 1].
Manav, Nesibe   +2 more
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

On Compactness of similarity orbits of norm-attainable, Operators [PDF]

open access: yes, 2019
Paper presented at the 5th Strathmore International Mathematics Conference (SIMC 2019), 12 - 16 August 2019, Strathmore University, Nairobi, KenyaThe notion of compactness plays an important role in analysis.
Ongati, Omolo   +2 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Approximation properties of a generalization of positive linear operators

open access: yes, 2008
In the present paper we introduce a generalization of positive linear operators and obtain its Korovkin type approximation properties. The rates of convergence of this generalization is also obtained by means of modulus of continuity and Lipschitz type ...
Dogru, OGÜN
core   +1 more source

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