Results 31 to 40 of about 6,585 (228)

On the convergence of sequences of positive linear operators and functionals on bounded function spaces [PDF]

open access: yes, 2021
Of concern are some simple criteria about the convergence of sequences of positive linear operators and functionals in the framework of spaces of bounded functions which are continuous on a given subset of their domain.
Francesco Altomare
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Banach Spaces of Analytic Vector-valued Functions [PDF]

open access: yes, 2007
The main theme of the thesis is the study of continuity and approximation problems, involving matrix-valued and vector-valued Hardy spaces on the unit disc ID and its boundary T in the complex plane.
Barclay, Steven John
core  

Coupling Harmonic Functions-Finite Elements for Solving the Stream Function-Vorticity Stokes Problem [PDF]

open access: yes, 2004
We consider the bidimensional Stokes problem for incompressible fluids in stream function-vorticity form. The classical finite element method of degree one usually used does not allow the vorticity on the boundary of the domain to be computed ...
Salaün, Michel   +2 more
core   +1 more source

The Existence and Uniqueness of the Solution of a Nonlinear Partial Differential Equation in the Eontinuous Functions of Holder and Sobolev Spaces

open access: yesپژوهش‌های ریاضی, 2020
Introduction Complex analysis is a comparatively active branch in mathematics which has grown significantly. A deep look at the implications of continuity, derivative and integral in complex analysis and their relation with partial differential equations
Mozhgan Akbari, Fateme Joveini
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Integral-type operators on continuous function spaces on the real line, [PDF]

open access: yes, 2008
In this paper we introduce and study a sequence of integral-type positive linear operators acting on a sufficiently large continuous function space which contains wide classes of weighted spaces of continuous functions on the real line.
MILELLA S.   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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