Results 41 to 50 of about 6,585 (228)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Parity and generalized multiplicity [PDF]

open access: yes, 1991
Assuming that X and Y are Banach spaces and that T is a path of linear Fredholm operators with invertible endpoints, in [F-Pl] we defined a homotopy invariant "the parity of T .
Fitzpatrickp.   +2 more
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

A global theory of algebras of generalized functions II: tensor distributions [PDF]

open access: yes, 2012
We extend the construction of [19] by introducing spaces of generalized tensor fields on smooth manifolds that possess optimal embedding and consistency properties with spaces of tensor distributions in the sense of L. Schwartz.
Steinbauer, Roland   +3 more
core  

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

A commutative noncommutative fractal geometry [PDF]

open access: yes, 2011
In this thesis examples of spectral triples, which represent fractal sets, are examined and new insights into their noncommutative geometries are obtained.
Samuel, Tony; id_orcid, Samuel, Anthony
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A function space model for canonical systems [PDF]

open access: yes, 2011
Recently, a generalization to the Pontryagin space setting of the notion of canonical (Hamiltonian) systems which involves a finite number of inner singularities has been given.
Woracek, H., Langer, Matthias
core  

Modified Fourier expansions: theory, construction and applications [PDF]

open access: yes, 2010
Modified Fourier expansions present an alternative to more standard algorithms for the approximation of nonperiodic functions in bounded domains. This thesis addresses the theory of such expansions, their effective construction and computation, and ...

core   +2 more sources

Operators acting in the dual spaces of discrete Cesàro spaces [PDF]

open access: yes, 2020
[EN] The discrete Cesaro (Banach) sequence spaces ces(r ...
Ricker, Werner J.   +3 more
core   +1 more source

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