Results 61 to 70 of about 6,585 (228)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Linear operators on $c_x$ [PDF]
, 1972 summary:In this note we study some properties concerning certain copies of the classic Banach space $c_{0}$ in the Banach space $\mathcal{L}\left( X,Y\right) $ of all bounded linear operators between a normed space $X$ and a Banach space $Y$ equipped ...
Alexander, George M. +7 more
core +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Function spaces and multiplier operators [PDF]
, 2001 Let G denote a locally compact Hausdorff abelian group. Then a bounded linear operator T from L^2(G) into L^2(G) is a bounded multiplier operator if, under the Fourier transform on L^2(G ), for each function f in L^2(G), T(f) changes into a bounded ...
S Okada (6917540) +1 more
core
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Composition operators on noncommutative Hardy spaces [PDF]
, 2011 In this paper we initiate the study of composition operators on the noncommutative Hardy space Hball2, which is the Hilbert space of all free holomorphic functions of the formf(X1,…,Xn)=∑k=0∞∑|α|=kaαXα,∑α∈Fn+|aα ...
Gelu Popescu, Popescu, Gelu
core +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
On the covering dimension of the set of solutions of some nonlinear equations [PDF]
, 1986 We prove an abstract theorem whose sole hypothesis is that the degree of a certain map is nonzero and whose parametric equations are studied using cohomological mconclusions imply sharp, multidimensional continuation results.
Pejsachowicz, Jacobo +4 more
core