Results 91 to 100 of about 20,481 (312)

Exploring a Novel Multi-Stage Differential Transform Method Coupled with Adomian Polynomials for Solving Implicit Nonlinear ODEs with Analytical Solutions

Mathematics
In engineering, physics, and other fields, implicit ordinary differential equations are essential to simulate complex systems. However, because of their intrinsic nonlinearity and difficulty separating higher-order derivatives, implicit ordinary ...
Brahim Benhammouda, Hector Vazquez-Leal
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

On solving periodic Riccati equations [PDF]

, 2008
Numerically reliable algorithms to compute the periodic non-negative definite stabilizing solutions of the periodic differential Riccati equation (PRDE) and discrete-time periodic Riccati equation (DPRE) are proposed. For the numerical solution of PRDEs,
A. Varga, Varga, Andreas
core   +1 more source

Stability criterion for linear systems of ordinary differential equations

, 2021
The Riccati equation method is used to establish a new stability criteria for linear systems of ordinary differential equations. Two examples are presented in which the obtained result is compared with the results obtained by the Lyapunov and Bogdanov methods, by a method involving estimates of solutions in the Lozinskii logarithmic norms and by the ...
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A numerical evaluation of solvers for the periodic Riccati differential equation [PDF]

, 2009
Efficient and accurate structure exploiting numerical methods for solving the periodic Riccati differential equation (PRDE) are addressed. Such methods are essential, for example, to design periodic feedback controllers for periodic control systems ...
Andras Varga, Varga, Andreas, Varga, Andras,, Varga, Andras, Sergei Gusev, Kagström, Bo, Anton Shiriaev, Gusev, Sergei,, Shiriaev, Anton,, Stefan Johansson, Johansson, Stefan, Shiriaev, Anton, Kågström, Bo,, Gusev, Sergei, Johansson, Stefan,   +14 more
core   +1 more source

System of linear ordinary differential and differential-algebraic equations and pseudo-spectral method

Computers & Mathematics with Applications, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
M. Saravi, Esmail Babolian, R. England, M. Bromilow   +3 more
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Solvlng Non-Linear First Order Ordinary Differential Equations. [PDF]

, 2022
The initial value problem for a first-order system of ordinary differential equations is that much emphasis is put on finding solutions for linear differential equations leaving out nonlinear ones.
Taremwa, Elias
core