Results 101 to 110 of about 20,481 (312)
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Numerical modelling of some systems in the biomedical sciences [PDF]
, 1998 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Finite-difference numerical methods are developed for the solution of some systems in the biomedical sciences; namely, a predator-prey model and the SEIR ...
Al-Showaikh, F.N.M., Al-Showaikh, Faisal
core
Geometric Linearization of Ordinary Differential Equations
Symmetry, Integrability and Geometry: Methods and Applications, 2007 The linearizability of differential equations was first considered by Lie for scalar second order semi-linear ordinary differential equations. Since then there has been considerable work done on the algebraic classification of linearizable equations and ...
Asghar Qadir
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
On tau functions associated with linear systems [PDF]
, 2012 \noindent {\bf Abstract} This paper considers the Fredholm determinant $\det (I-\Gamma_x)$ of a Hankel integral operator on $L^2(0, \infty )$ with kernel $\phi (s+t+2x)$, where $\phi$ is a matrix scattering function.
Samantha L. Newsham +3 more
core
Spectral equivalences, Bethe ansatz equations, and reality properties in PT-symmetric quantum mechanics [PDF]
, 2001 The one-dimensional Schrodinger equation for the potential x(6)+alphax(2)+l (l+1)/x(2) has many interesting properties. For certain values of the parameters I and a the equation is in turn supersymmetric (Witten) and quasi-exactly solvable (Turbiner ...
Dunning, Clare +2 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Equivalence of Linear Systems of Two Second-Order Ordinary Differential Equations [PDF]
, 2011 An equivalence problem is solved completely for a linear system of two second-order ordinary differential equations. Using Lie's infinitesimal method we construct the basis of differential invariants for this class of equations and provide the operators ...
Bagderina, Yulia Yu.
core +2 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source