Results 121 to 130 of about 2,594,240 (334)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Identification of nonlinear time-varying systems using an online sliding-window and common model structure selection (CMSS) approach with applications to EEG [PDF]
, 2010 The identification of nonlinear time-varying systems using linear-in-the-parameter models is investigated. A new efficient Common Model Structure Selection (CMSS) algorithm is proposed to select a common model structure.
Billings, S.A. +3 more
core
Linear Parameter-Varying and Fixed-Parameter H∞-Based Control of a Bearingless Compressor
IEEE AccessBearingless machines have the potential to provide shorter rotors and achieve overall lower losses and higher energy densities than traditional technologies. However, levitation control has to overcome some further challenges.
Andrei Zhuravlev +3 more
doaj +1 more source
Adaptive Model Predictive Control of a Two-wheeled Robot Manipulator with Varying Mass
Measurement + Control, 2018 This paper presents the adaptive model predictive control approach for a two-wheeled robot manipulator with varying mass. The mass variation corresponds to the robot picking and placing objects or loads from one place to another.
Mert Önkol, Coşku Kasnakoğlu
doaj +1 more source
Aerospace Science and Technology, 2019 The tilt rotor unmanned aerial vehicle (TRUAV) has attracted considerable attention in recent years, and its control design, particularly during the transition procedure, is still a challenge.
Zhong Liu +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Economic Linear Parameter Varying Model Predictive Control of the Aeration System of a Wastewater Treatment Plant. [PDF]
Sensors (Basel), 2022 Nejjari F +5 more
europepmc +1 more source
Digital fuzzy sliding-mode control for a linear parameter-varying air–fuel ratio system
Advances in Mechanical Engineering, 2019 Air–fuel ratio is a key factor for the minimization of the harmful pollutant emissions and maximization of fuel economy. However, a big challenge for air–fuel ratio control is a large time-varying delay existing in spark ignition engines. In this article,
Hsiu-Ming Wu, Reza Tafreshi
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source