Results 81 to 90 of about 85,913 (260)
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Notes On The Non Linear Operator Equation I AXAX n  ï€*
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2016 Necessary and sufficient conditions for the operator equation I AXAX n  ï€* , to have a real positive definite solution X are given. Based on these conditions, some properties of the operator A as well as relation between the solutions X ...
B.A. Ahmed, M.M. Hilal
doaj
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
On the modified beta approximating operators of second kind
Journal of Numerical Analysis and Approximation Theory, 2005 We shall define a general linear operator from which we obtain as particular case the modified beta second kind operator\[(T_{p,q}f)(x)=\frac{1}{B(p,q)}\int_0^\infty\tfrac{u^{p-1}}{(1+u)^{p+q}}f\left(\frac{B(p,q)}{B(p+a,q-a)}u^ax\right){\rm d}u.\] We ...
Vasile Miheşan
doaj +2 more sources
On summability and positive linear operators
Journal of Approximation Theory, 1979 AbstractQuantitative estimates for approximation by positive linear operators are obtained with the use of a summability method which includes both convergence and almost convergence.
openaire +2 more sources
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Use of identity of A. Hurwitz for construction of a linear positive operator of approximation
Journal of Numerical Analysis and Approximation Theory, 2002 By using a general algebraic identity of Adolf Hurwitz [1], which generalizes an important identity of Abel, we construct a new operator \(S_m^{(\beta_1,\ldots,\beta_m)}\) approximating the functions. A special case of this is the operator \(Q_m^\beta\)
Dimitrie D. Stancu
doaj +2 more sources
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source