Results 71 to 80 of about 8,015,484 (172)
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Compact well-bounded operators [PDF]
, 2001 Every compact well-bounded operator has a representation as a linear combination of disjoint projections reminiscent of the representation of compact self-adjoint operators. In this note we show that the converse of this result holds, thus characterizing
Qingping, C., Doust, I.
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Hypercyclic tuples of operators on $C^n$ and $R^n$ [PDF]
, 2012 A tuple $(T_1,\dots,T_n)$ of continuous linear operators on a topological vector space $X$ is called hypercyclic if there is $x\in X$ such that the the orbit of $x$ under the action of the semigroup generated by $T_1,\dots,T_n$ is dense in $X$.
Shkarin, Stanislav
core +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Infinitely Many Specific Fuzzy Neural Network Operators Treated as Fuzzy Positive Linear Operators
MathematicsBasic fuzzy multicomposite neural network operators are interpreted as fuzzy positive linear operators, and the related general fuzzy theory is applied. These fuzzy operators are defined by the composition of seven well-known activation functions. We are
George A. Anastassiou
doaj +1 more source
Transformation of the second order modulus by positive linear operators
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2015 We obtain estimates for the transformation of the second order modulus of continuity by positive linear operators which satisfy certain conditions, which are common to a large class of approximation operators.
Pǎltǎnea Radu, Stan Gabriel
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
A Theorem of Rolewicz's Type for Measurable Evolution Families in Banach Spaces [PDF]
, 2001 Let $varphi$ be a positive and non-decreasing function defined on the real half-line and ${mathcal U}$ be a strongly measurable, exponentially bounded evolution family of bounded linear operators acting on a Banach space and satisfing a certain ...
Constantin Buse +3 more
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source