Results 81 to 90 of about 986,527 (283)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The Carathéodory Pseudodistance and Positive Linear Operators

open access: yesInternational Journal of Mathematics, 1997
We give a new elementary proof of Lempert's theorem, which states that for convex domains the Carathéodory pseudodistance coincides with the Lempert function and thus with the Kobayashi pseudodistance. Moreover, we prove the product property of the Carathéodory pseudodistance.
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Approximating Derivatives by a Class of Positive Linear Operators

open access: yesInternational Journal of Analysis and Applications, 2013
Some Direct Theorems for the linear combinations of a new class of positive linear operators have been obtained for both, pointwise and uniform simultaneous approximations.
Bramha Dutta Pandey, B. Kunwar
doaj   +2 more sources

Reverses of Young and Heinz inequalities for positive linear operators

open access: yesJournal of Inequalities and Applications, 2016
Let A, B be invertible positive operators on a Hilbert space H. We present some improved reverses of Young type inequalities, in particular, ( 1 − ν ) 2 ν ( A ∇ B ) + ( 1 − ν ) 2 ( 1 − ν ) H 2 ν ( A , B ) ≥ 2 ( 1 − ν ) ( A ♯ B ) $$ (1-\nu)^{2\nu}(A\nabla
S Malekinejad, S Talebi, AG Ghazanfari
doaj   +1 more source

Positive linear operators continuous for strict topologies [PDF]

open access: yesProceedings of the American Mathematical Society, 1974
If A A is an S W SW algebra of real-valued functions on a set X X equipped with the weak topology for A A , and if A A separates its zero sets, then many results valued for C b (
openaire   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Approximation of twice differentiable functions by positive linear operators

open access: yesJournal of Numerical Analysis and Approximation Theory, 1985
Not available.
I. Raşa
doaj   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Preservers for the p-Norm of Linear Combinations of Positive Operators

open access: yesAbstract and Applied Analysis, 2014
We describe the structure of those transformations on certain sets of positive operators which preserve the p-norm of linear combinations with given nonzero real coefficients. These sets are the collection of all positive pth Schatten-class operators and
Gergő Nagy
doaj   +1 more source

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