Results 51 to 60 of about 64,350 (258)

Predictive coding networks for temporal prediction.

PLoS Computational Biology
One of the key problems the brain faces is inferring the state of the world from a sequence of dynamically changing stimuli, and it is not yet clear how the sensory system achieves this task.
Beren Millidge, Mufeng Tang, Mahyar Osanlouy, Nicol S Harper, Rafal Bogacz   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Line Spectral Frequency-based Noise Suppression for Speech-Centric Interface of Smart Devices

Advances in Electrical and Computer Engineering, 2011
This paper proposes a noise suppression technique for speech-centric interface of various smart devices. The proposed method estimates noise spectral magnitudes from line spectral frequencies (LSFs), using the observation that adjacent LSFs correspond ...
SEO, Y. H., KIM, J. H., PARK, J. S., JANG, G. J.   +3 more
doaj   +1 more source

Pattern recognition applying LDA and LR to optoelectronic signals of optical scanning systems

Revista Iberoamericana de Automática e Informática Industrial RIAI, 2020
This paper is a follow-up to previous researches already published regarding the minimization of optical-electrical noise in optical scanning systems OSS, by the implementation of computational techniques for pattern recognition generated by each ...
J. E. Miranda-Vega, M. Rivas-López, W. Flores-Fuentes, O. Sergiyenko, L. Lindner, J. C. Rodríguez-Quiñonez   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

LPRLC: Linear predictive run length coding to improve energy consumption of wireless body area networks

Results in Engineering
A Wireless Body Area Network (WBAN) is a collection of sensors that play a significant role in healthcare. These sensors are designed in small sizes for sending and receiving data.
Mahdieh Hajiloo Vakil, Zahra Shirmohammadi   +1 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Evaluation of a warped linear predictive coding scheme [PDF]

2000 IEEE International Conference on Acoustics, Speech, and Signal Processing. Proceedings (Cat. No.00CH37100), 2002
Basically all conventional digital signal processing techniques can be warped by introducing a simple modification to the system. In this paper, the focus is in warped linear predictive coding techniques with application to speech and audio coding. The performance of warped LPC is compared with a conventional LPC in listening tests and in terms of ...
openaire   +1 more source