Results 121 to 130 of about 4,755,611 (236)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Investigation the effect of different ionic liquids based-aryl imidazole on the onset precipitation of asphaltene. [PDF]

Sci Rep, 2023
El-Nagar RA, Nessim MI, Ismail DA, Mohamed MG, Ghanem A.   +4 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Mathematical methods to model double strip cylindrical fruit preserver using water as heat absorber. [PDF]

Sci Rep
Nega T.
europepmc   +1 more source

Binary Graph Labelings and Linear Preservers

Journal of Algebra Combinatorics Discrete Structures and Applications
An FM labeling of the vertices of an undirected graph requires that half the neighbors of each vertex are labeled zero and the other half labeled one. Variations of this type of labeling are presented and examples of the smallest and largest of graphs having one of these FM labelings are given.
openaire   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Anti-Icing Organogel Enables Quasi-Homogeneous Supercooling Preservation of Mouse Hearts. [PDF]

Adv Sci (Weinh)
Li J, Wang W, Li C, Kuang L, Huang Z, Chen X, Guo Z, Liu K, Liu J.   +8 more
europepmc   +1 more source

Duality between some linear preserver problems. II. Isometries with respect to c-special norms and matrices with fixed singular values

, 1988
Chi-Kwong Li, N. Tsing
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Freely foraging macaques value information in ambiguous terrains. [PDF]

Sci Rep
Shahidi N, Ahmed Z, Badayeva Y, Lacal I, Gail A.   +4 more
europepmc   +1 more source