Results 51 to 60 of about 4,755,611 (236)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Linear mappings preserving ρ-orthogonality

open access: yesJournal of Mathematical Analysis and Applications, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Linear Satisfiability Preserving Assignments

open access: yesJournal of Artificial Intelligence Research, 2018
In this paper, we study several classes of satisfiability preserving assignments to the constraint satisfaction problem (CSP). In particular, we consider fixable, autark and satisfying assignments. Since it is in general NP-hard to find a nontrivial (i.e., nonempty) satisfiability preserving assignment, we introduce linear satisfiability preserving ...
Kei Kimura, Kazuhisa Makino
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Linear maps preserving commutativity

open access: yesLinear Algebra and its Applications, 1987
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Choi, M.D., Jafarian, A.A., Radjavi, H.
openaire   +1 more source

Linear Mappings that Preserve Potent Operators [PDF]

open access: yesProceedings of the American Mathematical Society, 1995
Summary: Let \(H\) and \(K\) be complex Hilbert spaces, while \({\mathcal B}(H)\) and \({\mathcal B}(K)\) denote the algebras of all linear bounded operators on \(H\) and \(K\), respectively. We characterize surjective linear mappings from \({\mathcal B}(H)\) onto \({\mathcal B}(K)\) that preserve potent operators in both directions.
Omladič, Matjaž, Šemrl, Peter
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Outer preserving linear operators

open access: yesJournal of Functional Analysis, 2011
The authors investigate bounded linear operators acting on the Hardy space \(H^2\) of analytic functions on the unit disc \(\mathbb{D}\) which preserve the set of \textit{shifted outer functions}. Recall that \(H^2\cong \ell^2(\mathbb{Z}_+)\), the isomorphism is given by \(\vec{a} = (a_k) \leftrightarrow f: f(z) = \sum_k a_k z^k\).
Gibson, P.C.   +2 more
openaire   +2 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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