Results 101 to 110 of about 283 (216)

Novel Escherichia coli-Infecting Bacteriophages Isolated from Uganda That Target Human Clinical Isolates. [PDF]

open access: yesPhage (New Rochelle), 2023
Nale JY   +37 more
europepmc   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

The 15-Year Survival Advantage: Immune Resilience as a Salutogenic Force in Healthy Aging. [PDF]

open access: yesAging Cell
Manoharan MS   +30 more
europepmc   +1 more source

Binary Graph Labelings and Linear Preservers

open access: yesJournal of Algebra Combinatorics Discrete Structures and Applications
An FM labeling of the vertices of an undirected graph requires that half the neighbors of each vertex are labeled zero and the other half labeled one. Variations of this type of labeling are presented and examples of the smallest and largest of graphs having one of these FM labelings are given.
openaire   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Exploring obesity phenotypes: a longitudinal perspective. [PDF]

open access: yesRev Endocr Metab Disord
Rosero-Revelo R   +6 more
europepmc   +1 more source

Characterization of cell-fate decision landscapes by estimating transcription factor dynamics. [PDF]

open access: yesCell Rep Methods, 2023
Jiménez S   +4 more
europepmc   +1 more source

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