Results 111 to 120 of about 306 (236)

Connectivity Labeling in Faulty Colored Graphs. [PDF]

Distrib Comput
Petruschka A, Sapir S, Tzalik E.
europepmc   +1 more source

Characterization of cell-fate decision landscapes by estimating transcription factor dynamics. [PDF]

Cell Rep Methods, 2023
Jiménez S, Schreiber V, Mercier R, Gradwohl G, Molina N.   +4 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Robust Material Properties in Epitaxial In₂Te₃ Thin Films across Varying Thicknesses. [PDF]

Small
Buchta M, Hoff F, Bothe L, Penner N, Ringkamp C, Schmidt T, Köttgen J, Veslin T, Mak KL, Frank J, Kim D, Wuttig M.   +11 more
europepmc   +1 more source

An Efficient Triplex TaqMan Quantitative PCR to Detect a Blackleg-Causing Lineage of Pectobacterium brasiliense in Potato Based on a Pangenome Analysis. [PDF]

Microorganisms, 2023
van der Lee TAJ, van Gent-Pelzer MPE, Jonkheer EM, Brankovics B, Houwers IM, van der Wolf JM, Bonants PJM, van Duivenbode I, Vreeburg RAM, Nas M, Smit S.   +10 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Collective privacy recovery: Data-sharing coordination via decentralized artificial intelligence. [PDF]

PNAS Nexus
Pournaras E, Ballandies MC, Bennati S, Chen CF.   +3 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

The cone of nonnegative polynomials with nonnegative coefficients and linear operators preserving this cone

Open Mathematics, 2014
Katkova Olga, Vishnyakova Anna
doaj   +1 more source

Advances in drug delivery systems, challenges and future directions. [PDF]

Heliyon, 2023
Ezike TC, Okpala US, Onoja UL, Nwike CP, Ezeako EC, Okpara OJ, Okoroafor CC, Eze SC, Kalu OL, Odoh EC, Nwadike UG, Ogbodo JO, Umeh BU, Ossai EC, Nwanguma BC.   +14 more
europepmc   +1 more source