Results 131 to 140 of about 306 (236)

Natural Epithelial Barrier Integrity Enhancers-Citrus medica and Origanum dayi Extracts. [PDF]

Gels
Coopersmith S, Rahamim V, Drori E, Miloslavsky R, Kozlov R, Gorelick J, Azagury A.   +6 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The impact of technological advancement on culture and society. [PDF]

Sci Rep
Alsaleh A.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Evaluation of Salmonella biofilm attachment and hydrophobicity characteristics on food contact surfaces. [PDF]

BMC Microbiol
Ivers C, Kaya EC, Yucel U, Boyle D, Trinetta V.   +4 more
europepmc   +1 more source

Removing unwanted variation from large-scale RNA sequencing data with PRPS. [PDF]

Nat Biotechnol, 2023
Molania R, Foroutan M, Gagnon-Bartsch JA, Gandolfo LC, Jain A, Sinha A, Olshansky G, Dobrovic A, Papenfuss AT, Speed TP.   +9 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

<i>Acanthamoeba castellanii</i> as a model for unveiling <i>Campylobacter jejuni</i> host-pathogen dynamics. [PDF]

Front Cell Infect Microbiol
Nasher F, Lehri B, Stabler RA, Wren BW.
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

BatchEval Pipeline: batch effect evaluation workflow for multiple datasets joint analysis. [PDF]

GigaByte
Zhang C, Zhang C, Kang Q, Li M, Xie H, Fang S, Xu X.   +6 more
europepmc   +1 more source