Results 111 to 120 of about 283 (216)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Robust Material Properties in Epitaxial In₂Te₃ Thin Films across Varying Thicknesses. [PDF]

Small
Buchta M, Hoff F, Bothe L, Penner N, Ringkamp C, Schmidt T, Köttgen J, Veslin T, Mak KL, Frank J, Kim D, Wuttig M.   +11 more
europepmc   +1 more source

An Efficient Triplex TaqMan Quantitative PCR to Detect a Blackleg-Causing Lineage of Pectobacterium brasiliense in Potato Based on a Pangenome Analysis. [PDF]

Microorganisms, 2023
van der Lee TAJ, van Gent-Pelzer MPE, Jonkheer EM, Brankovics B, Houwers IM, van der Wolf JM, Bonants PJM, van Duivenbode I, Vreeburg RAM, Nas M, Smit S.   +10 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The cone of nonnegative polynomials with nonnegative coefficients and linear operators preserving this cone

Open Mathematics, 2014
Katkova Olga, Vishnyakova Anna
doaj   +1 more source

Collective privacy recovery: Data-sharing coordination via decentralized artificial intelligence. [PDF]

PNAS Nexus
Pournaras E, Ballandies MC, Bennati S, Chen CF.   +3 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Post-earthquake emotional and behavioral problems in children: parent experiences, coping strategies, and predictive factors. [PDF]

Front Psychol
Tunç Y, Çelik OT, Kaçmaz C.
europepmc   +1 more source

Advances in drug delivery systems, challenges and future directions. [PDF]

Heliyon, 2023
Ezike TC, Okpala US, Onoja UL, Nwike CP, Ezeako EC, Okpara OJ, Okoroafor CC, Eze SC, Kalu OL, Odoh EC, Nwadike UG, Ogbodo JO, Umeh BU, Ossai EC, Nwanguma BC.   +14 more
europepmc   +1 more source