Results 61 to 70 of about 10,510,472 (349)
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
The essential multiobjectivity of linear programming
ORiON, 2007 It is argued that any non-trivial real world problems involve multiple objectives. The simplistic approach of combining objectives in linear form can generate highly misleading and biased results, and is poor operational research practice.
TJ Stewart
doaj +1 more source
Lexicographic Methods for Fuzzy Linear Programming
Mathematics, 2020 Fuzzy Linear Programming (FLP) has addressed the increasing complexity of real-world decision-making problems that arise in uncertain and ever-changing environments since its introduction in the 1970s.
Boris Pérez-Cañedo +3 more
doaj +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
A New Algorithm for Privacy-Preserving Horizontally Partitioned Linear Programs
Journal of Mathematics, 2021 In a linear programming for horizontally partitioned data, the equality constraint matrix is divided into groups of rows. Each group of the matrix rows and the corresponding right-hand side vector are owned by different entities, and these entities are ...
Chengxue Zhang +3 more
doaj +1 more source
Linear and non-linear optimization models for the selection of investment portfolio
Lietuvos Matematikos Rinkinys, 2021 This research suggests a maxmin model for the selection of investment portfolios. The risk evaluation coefficients are introduced. The components of portfolio are found by solving linear programming task in onemodel and non-linear programming task in the
Sigutė Vakrinienė +1 more
doaj +1 more source
Economic modelling using constraint logic programming [PDF]
, 1996 This paper investigates the use of constraint logic programming (CLP) in economic modelling through the design and implementation of two economic models.
Donovan, N, Gilbert, D
core
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Linear Programming Relaxations of Quadratically Constrained Quadratic Programs
, 2011 We investigate the use of linear programming tools for solving semidefinite programming relaxations of quadratically constrained quadratic problems. Classes of valid linear inequalities are presented, including sparse PSD cuts, and principal minors PSD ...
Belotti, Pietro +2 more
core +2 more sources