Results 71 to 80 of about 1,009,619 (268)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

MIN-MAX SOLUTIONS FOR PARAMETRIC CONTINUOUS STATIC GAME UNDER ROUGHNESS (PARAMETERS IN THE COST FUNCTION AND FEASIBLE REGION IS A ROUGH SET)

Ural Mathematical Journal, 2020
Any simple perturbation in a part of the game whether in the cost function and/or conditions is a big problem because it will require a game re-solution to obtain the perturbed optimal solution.
Yousria A. Aboelnaga, Mai Zidan
doaj   +1 more source

Linear Programming-Based Power Management for a Multi-Feeder Ultra-Fast DC Charging Station [PDF]

, 2023
Luigi Rubino, Guido Rubino, Raffaele Esempio   +2 more
openalex   +1 more source

OPTIMALITY AND SEPARABLE LINEAR PROGRAMMING: AN ADDITIONAL REMINDER [PDF]

The assumed global optimum solution obtained in linear programming is not an assumed characteristic of separable linear programming. Separable programming is non-linear programming and must possess certain sufficient conditions for a global optimum to be
Kilmer, Richard L.
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

A Case Study on Solutions of Linear Fractional Programming Problems

, 2023
Rashmi Ranjan Ota, Swetarani Tripathy, Mitali Madhusmita Nayak   +2 more
openalex   +1 more source

Reoptimizations in linear programming [PDF]

Replacing a real process which we are concerned in with other more convenient for the study is called modeling. After the replacement, the model is analyzed and the results we get are expanded on that process.
Albici, Mihaela, Tenovici, Cristina, Teselios, Delia   +2 more
core   +1 more source