Results 101 to 110 of about 1,688,491 (311)
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Local Linear Multivariate Regression with Variable Bandwidth in the Presence of Heteroscedasticity [PDF]
We present a local linear estimator with variable bandwidth for multivariate nonparametric regression. We prove its consistency and asymptotic normality in the interior of the observed data and obtain its rates of convergence.
Zinai Li, Azhong Ye, Rob J Hyndman
core
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Distributed Sparse Linear Regression
The Lasso is a popular technique for joint estimation and continuous variable selection, especially well-suited for sparse and possibly under-determined linear regression problems. This paper develops algorithms to estimate the regression coefficients via Lasso when the training data are distributed across different agents, and their communication to a
Gonzalo Mateos +2 more
openaire +2 more sources
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Fast Minimum Error Entropy for Linear Regression
The minimum error entropy (MEE) criterion finds extensive utility across diverse applications, particularly in contexts characterized by non-Gaussian noise.
Qiang Li +5 more
doaj +1 more source
On identification methods of linear regression models
The aim of this paper is to discus the efficiency of the least squares and least absolute values estimation methods, in such situations, then the sample is with outliers, the variance of the residuals changes in the time and the residuals are correlated.
Romualdas Salėtis
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
An Entropic Approach to Constrained Linear Regression
We introduce a novel entropy minimization approach for the solution of constrained linear regression problems. Rather than minimizing the quadratic error, our method minimizes the Fermi–Dirac entropy, with the problem data incorporated as constraints. In
Argimiro Arratia, Henryk Gzyl
doaj +1 more source

