Results 61 to 70 of about 1,688,491 (311)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A study of partial F tests for multiple linear regression models [PDF]
, 2007 Partial F tests play a central role in model selections in multiple linear regression models. This paper studies the partial F tests from the view point of simultaneous confidence bands.
Jamshidian, M. +4 more
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Minimum area confidence set optimality for confidence bands in simple linear regression [PDF]
, 2007 The average width of a simultaneous confidence band has been used by several authors (e.g. Naiman, 1983, 1984, Piegorsch, 1985a) as a criterion for the comparison of different confidence bands.
Liu, W., Hayter, A.J.
core +1 more source
LINEAR REGRESSION WITH R AND HADOOP [PDF]
Challenges of the Knowledge Society, 2015 In this paper we present a way to solve the linear regression model with R and Hadoop using the Rhadoop library. We show how the linear regression model can be solved even for very large models that require special technologies.
Bogdan OANCEA
doaj
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Improved Penalty Strategies in Linear Regression Models
Revstat Statistical Journal, 2017 We suggest pretest and shrinkage ridge estimation strategies for linear regression models. We investigate the asymptotic properties of suggested estimators.
Bahadır Yüzbaşı +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
OPLS statistical model versus linear regression to assess sonographic predictors of stroke prognosis
Neuropsychiatric Disease and Treatment, 2012 Kianoush Fathi Vajargah,1 Homayoun Sadeghi-Bazargani,2,3 Robab Mehdizadeh-Esfanjani,4 Daryoush Savadi-Oskouei,4 Mehdi Farhoudi41Department of Statistics, Islamic Azad University, Tehran, North Branch, 2Neuroscience Research Center, Department of ...
Fathi Vajargah K +4 more
doaj