Results 61 to 70 of about 6,070,042 (338)
CoRR, 2015 We consider the problem of fitting a linear model to data held by individuals who are concerned about their privacy. Incentivizing most players to truthfully report their data to the analyst constrains our design to mechanisms that provide a privacy guarantee to the participants; we use differential privacy to model individuals' privacy losses.
Cummings, Rachel +2 more
openaire +4 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Kernel Density Estimated Linear Regression
Proceedings of the International Florida Artificial Intelligence Research Society ConferenceRegression analysis is a cornerstone of predictive modeling, with linear regression and kernel regression standing as two of its most prominent paradigms.
Roshan Kalpavruksha +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Química Nova, 1997 The least square method is analyzed. The basic aspects of the method are discussed. Emphasis is given in procedures that allow a simple memorization of the basic equations associated with the linear and non linear least square method, polinomial ...
Rogério Custodio +2 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
LINEAR REGRESSION WITH R AND HADOOP [PDF]
Challenges of the Knowledge Society, 2015 In this paper we present a way to solve the linear regression model with R and Hadoop using the Rhadoop library. We show how the linear regression model can be solved even for very large models that require special technologies.
Bogdan OANCEA
doaj
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
OPLS statistical model versus linear regression to assess sonographic predictors of stroke prognosis
Neuropsychiatric Disease and Treatment, 2012 Kianoush Fathi Vajargah,1 Homayoun Sadeghi-Bazargani,2,3 Robab Mehdizadeh-Esfanjani,4 Daryoush Savadi-Oskouei,4 Mehdi Farhoudi41Department of Statistics, Islamic Azad University, Tehran, North Branch, 2Neuroscience Research Center, Department of ...
Fathi Vajargah K +4 more
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