Results 141 to 150 of about 1,319,586 (359)

Forecasting with missing data: Application to a real case [PDF]

open access: yes
This paper presents a comparative analysis of linear and mixed models for short term forecasting of a real data series with a high percentage of missing data. Data are the series of significant wave heights registered at regular periods of three hours by
Ana Justel, Pedro Delicado
core  

PEMODELAN PERSENTASE PENDUDUK MISKIN DI KABUPATEN DAN KOTA DI JAWA TENGAH DENGAN PENDEKATAN MIXED GEOGRAPHICALLY WEIGHTED REGRESSION [PDF]

open access: yes, 2014
Regression analysis is a statistical analysis that models the relationship between the response variable and the predictor variable. Geographically Weighted Regression (GWR) is the development of linear regression with the added factor of the ...
Hakim, Arief Rachman
core  

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Error-Function-Based Penalized Quantile Regression in the Linear Mixed Model

open access: yesApplied Sciences
We study a novel Doubly penalized ERror Function regularized Quantile Regression (DERF-QR) in this paper. This is a method of variable selection by ERror Function (ERF) regularization in the linear effects model.
Zelin Hang, Xiuli He
doaj   +1 more source

Linear mixed effects models: misspecification of the covariance structure studied through simulation and applications to an environmental data set [PDF]

open access: yes, 2009
The longitudinal experimental design with continuous responses is common in many fields, particularly in the ecological sciences. Due to the complexities in the data, such as the correlation between measurements from the same subject, appropriate forms
Kirton, Alecia
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

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