Results 101 to 110 of about 5,788,827 (317)

Common pitfalls in statistical analysis: Linear regression analysis

open access: yesPerspectives in Clinical Research, 2017
In a previous article in this series, we explained correlation analysis which describes the strength of relationship between two continuous variables.
Rakesh Aggarwal, Priya Ranganathan
doaj   +1 more source

Linear Regression Model in Estimating Solar Radiation in Perlis

open access: yes, 2012
Statistical models for predicting the solar radiation have been developed. In any prediction of the solar radiation, an understanding of its characteristics is of fundamental importance.
S. F. Ibrahim   +5 more
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Connecting Model-Based and Model-Free Approaches to Linear Least Squares Regression

open access: yesStatistica
In a regression setting with a response vector and given regressor vectors, a typical question is to what extent the response is related to these regressors, specifically, how well it can be approximated by a linear combination of the latter.
Lutz Dümbgen, Laurie Davies
doaj   +1 more source

USE OF THE SIMPLE LINEAR REGRESSION MODEL IN MACRO-ECONOMICAL ANALYSES [PDF]

open access: yesRevista Română de Statistică, 2011
The article presents the fundamental aspects of the linear regression, as a toolbox which can be used in macroeconomic analyses. The article describes the estimation of the parameters, the statistical tests used, the homoscesasticity and ...
Constantin ANGHELACHE
doaj  

A Modified New Two-Parameter Estimator in a Linear Regression Model

open access: yesModelling and Simulation in Engineering, 2019
The literature has shown that ordinary least squares estimator (OLSE) is not best when the explanatory variables are related, that is, when multicollinearity is present. This estimator becomes unstable and gives a misleading conclusion.
Adewale F. Lukman   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

An Ordinal Regression Model using Dealer Satisfaction Data [PDF]

open access: yes
This article analyses dealer satisfaction data in the agricultural technology market in Germany. The dealers could rate their suppliers in the 'overall satisfaction' and in 38 questions which can be summarized in 8 dimensions. An ordinal regression model
Alexander Staus
core  

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