Results 61 to 70 of about 2,688,321 (280)
Error-Function-Based Penalized Quantile Regression in the Linear Mixed Model
Applied SciencesWe study a novel Doubly penalized ERror Function regularized Quantile Regression (DERF-QR) in this paper. This is a method of variable selection by ERror Function (ERF) regularization in the linear effects model.
Zelin Hang, Xiuli He
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Lasso Estimation of an Interval-Valued Multiple Regression Model
, 2015 A multiple interval-valued linear regression model considering all the cross-relationships between the mids and spreads of the intervals has been introduced recently.
A. Blanco-Fernández +6 more
core +1 more source
Linear regression model for investment analysis of an oil company
Revista Produção e Desenvolvimento, 2015 Changes in global economic environment meant that companies, particularly publicly traded, seek adaptations to global market model, which gives preference to the analysis of stock indicators profitability.
Edson Vinicius Pontes Bastos +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
A Two-way Crossed Effects Fuzzy Panel Linear Regression Model
International Journal of Computational Intelligence SystemsOver the last two decades, the panel data model has become a focus of applied research. While there are numerous proposals for soft regression models in the literature, only a few linear regression models have been proposed based on fuzzy panel data ...
Gholamreza Hesamian, Arne Johannssen
doaj +1 more source
Prediction of Gene Expression Patterns With Generalized Linear Regression Model
Frontiers in Genetics, 2019 Cell reprogramming has played important roles in medical science, such as tissue repair, organ reconstruction, disease treatment, new drug development, and new species breeding.
Shuai Liu +6 more
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source