Results 41 to 50 of about 422,318 (265)
In this paper, two sector beam scanning approaches (BSAs) based on element position perturbations (EPPs) in the azimuth plane are introduced. In EPP-BSA, the elements’ excitations are kept constant and the elements’ positions in the direction normal to ...
Safaa I. Abd Elrahman +3 more
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The comparative analysis results of various types of discriminators operating under linear scanning of the radiation pattern, as well as the single-pulse direction finding discriminator using the comparison amplitude method are presented.
M. M. Bulash, S. V. Shaliapin
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Considering the synthesis of the quasi-optimal two-channel discriminator structure of the angle meter of the fast fluctuating signal source for using a linear scanning of the antenna pattern. It is shown that the discriminator can be constructed by using
M. M. Bulash +2 more
doaj
Wide-angle scanning planar array with quasi-hemispherical-pattern elements
A compact quasi-hemispherical-pattern antenna, two linear wide-angle scanning arrays, and a planar wide-angle scanning array are proposed. To increase the field-of-view scanning range of arrays, a compact low-profile antenna with a quasi-hemispherical ...
Ren Wang +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
In order to improve comfort in abdominal ultrasound scanning, reduce operator dependency and increase image resolution, a novel method for automatic ultrasound cervix scanning, especially for developing countries, has been developed.
Christina Pahl
doaj +1 more source

