Results 91 to 100 of about 6,691 (217)

Antifibrotic effects of specific targeting of the 5‐hydroxytryptamine 2B receptor (5‐HT2BR) in murine models and ex vivo models of scleroderma skin

open access: yesArthritis &Rheumatology, Volume 77, Issue 8, Page 1063-1076, August 2025.
Objective Systemic sclerosis (SSc) is a connective tissue disease with fibrotic remodeling of the skin and various internal organs. SSc is associated with the highest case‐specific mortality of all rheumatic autoimmune diseases with limited antifibrotic treatment options.
Thuong Trinh‐Minh   +12 more
wiley   +1 more source

Case Report: Concomitant Uveitis and Linear Scleroderma in an Adult Patient

open access: bronze, 2021
LETÍCIA RESENDE BRANDÃO   +6 more
openalex   +1 more source

Monoclonal Gammopathies of Clinical Significance—Scleromyxedema: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Scleromyxedema is an uncommon, chronic connective tissue disorder with an obscure etiology. It is distinguished by fibromyxoid skin lesions and elevated serum monoclonal immunoglobulin levels. The condition's rarity limits epidemiological data, making prevalence and incidence assessment difficult.
Shanshan Liang   +4 more
wiley   +1 more source

Laboratory Practices for the Detection and Characterization of Cryoglobulins and Cryofibrinogen

open access: yesJournal of Clinical Laboratory Analysis, Volume 39, Issue 15, August 2025.
This study shows the importance of carrying out the search for both cryoproteins, cryoglobulins, and cryofibrinogen in cases of strong clinical suspicion of cryoproteinemia, despite their complex but not impossible detection. Use of correct procedures from the pre‐preanalytical phase up to reporting, of alternative methods such as immunotyping and the ...
Teresa Troiano   +5 more
wiley   +1 more source

Intestinal involvement in graft versus host disease in children: An overview by the ESPGHAN Gastroenterology Committee

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 81, Issue 2, Page 246-255, August 2025.
Abstract Graft versus host disease (GVHD) is a complication that frequently occurs after haematopoietic stem cell transplantation and concerns many children in paediatric haematology‐oncology and bone marrow transplantation departments. It can affect various organs, with the skin, gastrointestinal tract and liver being the most commonly involved.
Marina Vincent   +12 more
wiley   +1 more source

Adalimumab Monotherapy or Combination Therapy With Methotrexate in Paediatric Uveitis: Data From the AIDA Network Uveitis Registry

open access: yesClinical &Experimental Ophthalmology, Volume 53, Issue 6, Page 619-626, August 2025.
ABSTRACT Background The study objective was to compare the effectiveness of adalimumab (ADA) in monotherapy and in combination with methotrexate (MTX) for paediatric noninfectious uveitis (NIU). Methods Registry‐based observational study. Children receiving ADA for active uveitis were divided into the ADA monotherapy group (group 1) and the ADA plus ...
Carla Gaggiano   +40 more
wiley   +1 more source

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