Results 51 to 60 of about 10,463 (261)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Spaces generated by the cone of sublinear operators
This paper deals with a study on classes of non linear operators. Let $SL(X,Y)$ be the set of all sublinear operators between two Riesz spaces $X$ and $Y$. It is a convex cone of the space $H(X,Y)$ of all positively homogeneous operators.
A. Slimane
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
A General Approximation Approach for the Simultaneous Treatment of Integral and Discrete Operators
In this paper, we give a unitary approach for the simultaneous study of the convergence of discrete and integral operators described by means of a family of linear continuous functionals acting on functions defined on locally compact Hausdorff ...
Vinti Gianluca, Zampogni Luca
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
MEASURE OF NON-COMPACTNESS IN THE LORENTZ SPACES
Geometric characteristics of regular spaces are determined. Examples of regular spaces are the Lebesgue and Lorentz spaces, in particular. For the Lorentz spaces an inequality for arbitrary subsets, connecting the measures of noncompactness and are ...
N. A. Erzakova
doaj
Positive operators and approximation in function spaces on completely regular spaces
We discuss the approximation properties of nets of positive linear operators acting on function spaces defined on Hausdorff completely regular spaces. A particular attention is devoted to positive operators which are defined in terms of integrals with ...
Francesco Altomare, Sabrina Diomede
doaj +1 more source
On linear operators on ordered banach spaces [PDF]
The order structure of the space of all continuous linear operators on an ordered Banach space is studied. The main topic is the Robinson property, that is, the norm of a positive linear operator is attained on the positive unit cone.
openaire +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

