Results 221 to 230 of about 2,590,383 (288)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Stability analysis and numerical simulation of nonlocal extended epidemic models using positivity-preserving scheme. [PDF]

Sci Rep
Yousuf M, Alshakhoury N.
europepmc   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Advancements in aptasensors development for the detection of zearalenone. [PDF]

Front Nutr
Cheng S, Xu J, Gao P, Cai J, Cao Y, Hong Y, Ding H, Chen H, Liu X, Zhang G, Zhang T, Guo X, Xie K.   +12 more
europepmc   +1 more source

Development of machine learning surrogate models for slope stability prediction using AI techniques: a case study of the Meizhou landslide. [PDF]

Sci Rep
Khan MI, Fei J, Chen X, Hamza M.
europepmc   +1 more source

The effect of bilateral knee osteoarthritis on spatiotemporal gait parameters during incline walking: implications for gait rehabilitation. [PDF]

PeerJ
Wang Z, Hou Y, Yang L, Chien JH.
europepmc   +1 more source

Age-Related Increases in Graft Tendon Size and Stiffness During Skeletal Growth Enhance Anterior Cruciate Ligament Graft Function and Joint Stability in an Early Adolescent Porcine Model. [PDF]

J Biomech Eng
Zhang Y, Gurbuz K, Chavez-Arellano J, Opperman L, Spang JT, Fisher MB.   +5 more
europepmc   +1 more source