Results 81 to 90 of about 797,663 (268)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Stability of A Switched Linear System

Journal of Mechanical Engineering and Sciences, 2012
Hybrid systems are dynamic systems that arise out of the interaction of continuous state dynamics and discrete state dynamics. Switched systems, which are a type of hybrid system, have been given much attention by control systems research over the pastdecade.
At-Tasneem Mohd Amin, Sallehuddin Mohamed Haris, Zulkifli Mohd Nopiah   +2 more
openaire   +2 more sources

Local sign stability and its implications for spectra of sparse random graphs and stability of ecosystems

Journal of Physics: Complexity
We study the spectral properties of sparse random graphs with different topologies and type of interactions, and their implications on the stability of complex systems, with particular attention to ecosystems.
Pietro Valigi, Izaak Neri, Chiara Cammarota   +2 more
doaj   +1 more source

On the stability of a particular class of one-dimensional states of dynamic equilibrium of the Vlasov–Poisson electron gas

Учёные записки Казанского университета: Серия Физико-математические науки
The one-dimensional problem of the linear stability of dynamic states of local thermodynamic equilibria with respect to small perturbations was studied for the case when the Vlasov–Poisson electron gas contains electrons with a stationary distribution ...
Yu. G. Gubarev, M. S. Kotelnikova
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Determination of the Boundary of the “Diffusion–Gravitational Convection” Regimes Change in Three-Component Gas Mixtures Containing Real Gases, Taking into Account the Compressibility Factor of the Components Under Isothermal Conditions

Fluids
The stability analysis for isothermal three-component gas mixtures, in which one of the components exhibits real properties in the considered pressure range, is performed.
Vladimir Kossov, Olga Fedorenko, Holm Altenbach, Madina Tuken   +3 more
doaj   +1 more source

Linear stability analysis of chemical mechanism, Listanalchem: A tool for the search of spontaneous mirror symmetry breaking. [PDF]

MethodsX, 2023
Cruz E, Montoya A, Ágreda J.
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Identification of a window for quiescent H-mode operation in MHD stability diagram of DIII-D plasmas

Nuclear Fusion
A window for quiescent H-mode (QH-mode) operation in DIII-D plasmas in the diagram of pedestal magnetohydrodynamic (MHD) stability was identified through linear MHD stability analysis, accounting for the effects of plasma rotation and ion diamagnetic ...
N. Aiba, X. Chen, T.H. Osborne, K.H. Burrell   +3 more
doaj   +1 more source

Computational Oncology of Chemotaxis-Driven Tumour–Immune Spatial Patterning and Stability

Bioengineering
We develop a reaction–diffusion–chemotaxis model for spatial tumour–immune–chemokine dynamics that couples logistic tumour growth, immune-mediated killing, chemokine-dependent immune recruitment, chemotactic migration, and signal production.
Zonghao Liu, Jiguang Yu, Louis Shuo Wang, Lei Su, Ye Liang, Yang Du, Jingfeng Liu   +6 more
doaj   +1 more source