Results 161 to 170 of about 11,397,498 (302)

Automated loop invariant inference through learning-guided program structure analysis. [PDF]

PLoS One
Hadad AS, Zheng J, Ahmed AA, Saeed F, Alkhatib M, Mohammed SH.   +5 more
europepmc   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Interpretable Drug-Target Prediction via Geometric Alignment: A Linear Alternative to Deep Architectural Complexity. [PDF]

Mol Inform
Ghimire A, Alvin C, Bess A, Mukhopadhyay S.   +3 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

A Run-Length-Compressed Skiplist Data Structure for Dynamic GBWTs Supports Time- and Space-Efficient Pangenome Operations over Syncmers. [PDF]

J Comput Biol
Durbin R.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

NA-CDQuant: Quantitative spectral analysis of nucleic acid structure by circular dichroism spectroscopy. [PDF]

Proc Natl Acad Sci U S A
Mosca K, Hoffmann SV, Jones NC, Sinden RR, Wien F, Marco S, Arluison V.   +6 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Modelling conditional covariance structure in linear mixed models

, 2001
Modelling conditional covariance structure in linear mixed ...
MacKenzie, Gilbert, Pan, Jianxin, Jianxin Pan (647081), Gilbert Mackenzie (12348862)   +3 more
core  

BA-ARAP-NMA: A Local Geometry Control Nonlinear Normal-Mode Analysis Method. [PDF]

Biology (Basel)
Zhang Z, Liu D, Yu H, Ma LZ.
europepmc   +1 more source