Results 141 to 150 of about 1,576,829 (311)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Low-complexity trellis decoding of linear block codes. [PDF]
, 1995 The authors introduce a new simple encoding technique which allows the design of a wide variety of linear block codes. They present a number of examples in which the most widely used codes (Reed-Muller, Hamming, Golay, optimum etc.) have been designed ...
Markarian, G. S. +2 more
core
Causal Structures in Linear Spaces
, 1997 13 pages, PostScript, generated by Word 7.0 (300 dpi)
openaire +3 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
SLAC (Stanford Linear Accelerator Center) experiment E142 [PDF]
, 1990 Deep inelastic scattering experiments to measure the proton spin- dependent structure function were first pioneered in SLAC experiments in the 1970's (1). These early experiments established the existence of large asymmetries in the spin structure of the
Hughes, E.
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
A variance shilf model for outlier detection and estimation in linear and linear mixed models [PDF]
, 2008 Includes abstract.Includes bibliographical references.Outliers are data observations that fall outside the usual conditional ranges of the response data.They are common in experimental research data, for example, due to transcription errors or faulty ...
Gumedze, Freedom Nkhululeko
core
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
A new switched power linac structure [PDF]
, 1989 A new pulse power structure has been described that utilizes an easily accessible rectilinear switch. The new structure is more ''forgiving'' (as far as risetime is concerned) than the radial line transformer, and contains fewer switching structures/unit
Villa, F.
core