Results 121 to 130 of about 10,907,974 (296)
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Dynamic analysis of beam structure of linear vibrating screen
AIP AdvancesThis paper presents a novel model for calculating the dynamic stress of a beam structure in a vibrating screen. The proposed model employs a dynamic screen box model as a foundation and utilizes the flow method to establish the mass of the screening ...
Hui Long +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Orthogonal least squares methods and their application to non-linear system identification
, 1989 Identification algorithms based on the well-known linear least squares methods ofgaussian elimination, Cholesky decomposition, classical Gram-Schmidt, modifiedGram-Schmidt, Householder transformation, Givens method, and singular valuedecomposition are ...
Luo, W., Chen, Sheng, Billings, S. A.
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Chapter 5 Linear Logic Programming
, 2007 s depending on the characteristics of the language. A program in this setting is simply a collection of propositions that, through their form, will lead the proof search engine down a particular path, thereby achieving a particular computation.
Linear Logic Programming
core
Linear cryptanalysis of pseudorandom functions [PDF]
, 2015 Relatório de projeto de pesquisa.In this paper, we study linear relations propagating across block ciphers from the key input to the ciphertext (for a fixed plaintext block).
Freitas, Daniel Santana de +4 more
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