Results 101 to 110 of about 11,397,498 (302)
Linear collider development at SLAC
, 1993 Linear collider R&D at SLAC comprises work on the present Stanford Linear Collider (SLC) and work toward the next linear collider (NLC). Recent SLC developments are summarized. NLC studies are divided into hardware-based and theoretical. We report on the
Irwin, J.
core
Quasi-linear score for capturing heterogeneous structure in biomarkers
BMC Bioinformatics, 2017 Background Linear scores are widely used to predict dichotomous outcomes in biomedical studies because of their learnability and understandability. Such approaches, however, cannot be used to elucidate biodiversity when there is heterogeneous structure ...
Katsuhiro Omae +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Computation of H-infinity norm of linear discrete-time periodic systems [PDF]
, 2006 We propose an efficient an numerically reliable procedure for the computation of H-infinity norm of discrete-time linear periodic systems. The new procedure is general being applicable to both standard as well as descriptor periodic systems with time ...
Varga, Andreas
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Solving Linear Systems of Equations with Block Skyscraper Structure
Кібернетика та комп'ютерні технологіїThis paper proposes an efficient parallel algorithm for solving systems of linear algebraic equations (SLAE) using block skyscraper matrices, designed for execution on shared-memory computing systems.
Volodymyr Sydoruk +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Algebraic structure count of linear phenylenes and their congeners [PDF]
Journal of the Serbian Chemical Society, 2003 The algebraic structure count of the linear phenylene with h six-membered rings is known to be equal to h + 1. We show that the same expression applies if each four-membered ring in the phenylene is replaced by a linear array consisting of k four ...
IVAN GUTMAN
doaj
Cascade Structure for Finite Impulse Response Filters and Linear Prediction
Ingenius: Revista de Ciencia y Tecnología, 2012 This paper presents a complete analysis of the cascade structure for adaptive transversal filters based on adaptive algorithms. The standard structure of the cascade transversal FIR filter is obtained by replacing the whole structure by small ones with ...
Walter Humberto Orozco Tupacyupanqui
doaj +1 more source