Results 131 to 140 of about 5,163,492 (280)
On Some Problems of Trajectory Beam Program Control. Part II
Известия Иркутского государственного университета: Серия "Математика"The paper considers the problems of macroparameter control in a linear dynamic system. In the authors’ previous paper, such problems in controlling nonlinear systems were investigated.
D.A. Ovsyannikov, E. D. Kotina
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Resilient Reachability for Linear Systems. [PDF]
IFAC Pap OnLine, 2020 Bouvier JB, Ornik M.
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Non-commensurate fractional linear systems: New results. [PDF]
J Adv Res, 2020 Ortigueira MD, Bengochea G.
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
International Journal of Applied Mathematics and Computer ScienceThis paper addresses the construction of observable and maximum distance profile convolutional codes over finite fields that exhibit good performance with some available decoding algorithms for convolutional codes. Our construction is based on the use of
Decastro-García Noemí +2 more
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A linear systems approach to protect the night sky: implications for current and future regulations. [PDF]
R Soc Open Sci, 2020 Falchi F, Bará S.
europepmc +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source