Results 151 to 160 of about 12,755,747 (299)

Resilient Reachability for Linear Systems. [PDF]

open access: yesIFAC Pap OnLine, 2020
Bouvier JB, Ornik M.
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Identification of nonlinear interconnected systems [PDF]

open access: yes, 2009
This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.In this work we address the problem of identifying a discrete-time nonlinear system composed of a linear dynamical system connected to a static nonlinear ...
Pepona, Eleni
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Linear complementarity systems [PDF]

open access: yes, 1997
We introduce a new class of dynamical systems called "linear complementarity systems." The time evolution of these systems consists of a series of continuous phases separated by "events" which cause a change in dynamics and possibly a
Heemels, W.P.M.H.   +2 more
openaire   +4 more sources

The Open-Loop Discounted Linear Quadratic Differential Game for Regular Higher Order Index Descriptor Systems [PDF]

open access: yes
In this paper we consider the discounted linear quadratic differential game for descriptor systems that have an index larger than one. We derive both necessary and sufficient conditions for existence of an open-loop Nash (OLN) equilibrium.
Salmah, Y.   +2 more
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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