Results 91 to 100 of about 64,093 (287)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Healing responses at the angle after micro-invasive glaucoma surgery-an AS-OCT study.

PLoS ONE
PurposeTo evaluate structural alterations and healing responses in the trabecular meshwork region with optical coherence tomography (AS-OCT) following after gonioscopy assisted transluminal trabeculotomy (GATT) and microincisional trabeculectomy (MIT ...
Aparna Rao, Sujoy Mukherjee
doaj   +1 more source

The Influence of Substrate Structure on Membrane Adhesion

, 1999
We consider a membrane both weakly and strongly adhering to a geometrically structured substrate. The interaction potential is assumed to be local, via the Deryagin approximation, and harmonic.
Andelman, David, Swain, P. S.
core   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Free Surface Thin Film Flow of a Sisko’s Fluid over a Surface Topography

Journal of Applied Fluid Mechanics, 2017
The flow of a thin film down an inclined surface over topography is considered for the case of liquids with Sisko’s model viscosity. For the first time lubrication theory is used to reduce the governing equations to a non-linear evolution equation for a ...
R. A. Shah, P. Gaskel, S. Veremieiev
doaj  

Space-division multiplexing for fiber-wireless communications

, 2018
We envision the application of optical Space-division Multiplexing (SDM) to the next generation fiber-wireless communications as a firm candidate to increase the end user capacity and provide adaptive radiofrequency-photonic interfaces.
Barrera, David, Garcia, Sergi, Gasulla, Ivana, Hervas, Javier, Sales, Salvador   +4 more
core   +1 more source

Neotectonics of the Sumatran fault, Indonesia [PDF]

, 2000
The 1900-km-long, trench-parallel Sumatran fault accommodates a significant amount of the right-lateral component of oblique convergence between the Eurasian and Indian/Australian plates from 10°N to 7°S.
Natawidjaja, Danny, Sieh, Kerry
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A multiphase seismic investigation of the shallow subduction zone, southern North Island, New Zealand [PDF]

, 2001
The shallow structure of the Hikurangi margin, in particular the interface between the Australian Plate and the subducting Pacific Plate, is investigated using the traveltimes of direct and converted seismic phases from local earthquakes.
Aki, Ansell, Ansell, Anya M. Reading, Bannister, Barnes, Barnes, Bradshaw, Brisbourne, Chanier, David Gubbins, Davy, de Boor, Eberhart-Phillips, Eberhart-Phillips, Franklin, Gledhill, Gubbins, Helffrich, Helffrich, Iidaka, Lancaster, Lodge, Luyendyk, Mao, Marson-Pidgeon, Powell, Reading, Robinson, Samson, Smith, Smith, Smith, Spencer, Stuart, Walcott, Weijian Mao, Wessel, Wood   +38 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source