Results 71 to 80 of about 361,019 (310)

Oil Price Shocks: Testing for Non-linearity [PDF]

open access: yes
This paper presents evidence of a non-linear relationship between GDP growth and oil price changes in the US economy. We also argue that this non-linearity is not merely due to the use of data from the mid-1980s onwards, as most authors, so far, seem to ...
Rebeca Jiménez-Rodríguez
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Development of a Measurement Device for Micro Gas Flowrate Based on Laminar Flow Element with Micro-Curved Surface

open access: yesMicromachines
The laminar flow meter (LFM) boasts several advantages such as no moving parts, a wide range ratio, high measurement accuracy, quick dynamic response, etc., and is a promising technology for micro gas flow measurement.
Zixuan Wang   +4 more
doaj   +1 more source

Non-Linearity Effect of Energy Consumption on Economic Growth: Panel ASEAN-4 Countries [PDF]

open access: yes, 2020
The aim of the study is to investigate the impact of energy consumption on economic growth in ASEAN-4 countries as a whole. In addition, the effect of the non-linearity of the relationship between energy consumption and growth is examined using Threshold
Audrey, Liwan   +3 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Validation of the procedure for determination of amino acids composition of glatiramer acetate by C-13 NMR spectroscopy

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
The article describes validation of the procedure for determination of amino acids composition of glatiramer acetate by C-13 NMR spectroscopy. The procedure makes it possible to determine the molar ratio of amino acids present in glatiramer acetate with ...
N. E. Kuz’Mina   +6 more
doaj  

Signaling pathways as linear transmitters

open access: yeseLife, 2018
One challenge in biology is to make sense of the complexity of biological networks. A good system to approach this is signaling pathways, whose well-characterized molecular details allow us to relate the internal processes of each pathway to their input ...
Harry Nunns, Lea Goentoro
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Robustness of power properties of non-linearity tests [PDF]

open access: yes, 2012
The paper examines the robustness of the size and power properties of the standard non-linearity tests under different conditions such as moment failure and asymmetry of innovations. Our results reveal the following. First, there seems not to be a direct
Vavra, Marian
core   +3 more sources

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