Results 61 to 70 of about 361,019 (310)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
High linearity microstrip bandpass filter with electronically tunable notch
, 2013 A high linearity reconfigurable bandpass filter embedded with a tunable notch structure has been presented for future wideband wireless communication applications. A single varactor diode (BB135-NXP) is used for the purpose of tuning the notch.
Budimir, D. +2 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
On effective linearity of soil process models
, 2008 There are various circumstances in which it is important to know whether we can treat a model of a soil process as linear with respect to its parameters.
Corstanje, R., Lark, R. M.
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Shifting lines in D. H. Lawrence’s travel writings
E-READ.H. Lawrence (1885-1930) spent much of his life travelling around the globe, at least until his untimely death from tuberculosis. But Lawrence’s travel writing was inextricably linked with his personal philosophy, and one aspect that particularly ...
Tim GUPWELL
doaj +1 more source
Calibration – an under-appreciated component in the analytical process of the medical laboratories
Advances in Laboratory Medicine, 2023 Calibration of an analytical measurement procedure is an important basis for the reliability of patient results. Many publications and as well as procedures on how to estimate quality control and interpret those results have been become available over ...
Sonntag Oswald, Loh Tze Ping
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Flexible linearity profile low noise feedforward amplifiers for improving channel capacity [PDF]
, 2003 This paper describes a highly linear low noise amplifier (LNA) exhibiting a flexible linearity profile intended as a way to meet future flexible mobile communications standards.
Watkins, GT, Warr, PA
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source